5-FLUOROURACIL - (51-21-8)

Introduction

Name: 5-fluorouracil; 5-fluoro-1H,3H-pyrimidine-2,4-dione*; Efudex
* IUPAC
CAS Number: 51-21-8
Chemical Formula: C4H3FN2O2
Molar Mass: 130.0772232 g
Mass Percent: C 36.934 %; H 2.3246 %; F 14.605 %; N 21.535 %; O 24.599 % 

Classification

• organic

Uses/Function

• "A variety of chemicals may be used to selectively kill cells that are in the process of dividing. The compound 5-fluorouracil, for example...is mistaken by the cancer cell for the nucleotide base uracil. Once incorporated into the DNA of the cancer cell, 5-fluorouracil's non-nucleotide structure interferes with the normal DNA workings, and the cell dies." 1

Bonding

For More Information

Sources

(1) - Suchocki, John. Conceptual Chemistry: Understanding Our World of Atoms and Molecules; Addison Wesley: San Francisco, California, 2001; pp 449-450.